Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model

Mice subcutaneously injected with bleomycin, an experimental model for human systemic sclerosis, develop skin and lung fibrosis, which is mediated by inflammatory cell infiltration. This process is highly regulated by multiple adhesion molecules. To assess the role of adhesion molecules in this path...

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Main Authors: Yoshizaki, Ayumi, Yanaba, Koichi, Iwata, Yohei, Komura, Kazuhiro, Ogawa, Asako, Akiyama, Yuichiro, Muroi, Eiji, Hara, Toshihide, Ogawa, Fumihide, Takenaka, Motoi, Shimizu, Kazuhiro, Hasegawa, Minoru, Fujimoto, Manabu, Tedder, Thomas F., Sato, Shinichi
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733122/
https://ncbi.nlm.nih.gov/pubmed/20624949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901778
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