Pharmacology and Safety of Glycerol Phenylbutyrate in Healthy Adults and Adults with Cirrhosis

Phenylbutyric acid (PBA), which is approved for treatment of urea cycle disorders (UCDs) as sodium phenylbutyrate (NaPBA), mediates waste nitrogen excretion via combination of PBA-derived phenylacetic acid with glutamine to form phenylactylglutamine (PAGN) that is excreted in urine. Glycerol phenylb...

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Detalhes bibliográficos
Main Authors: MCGuire, Brendan M., Zupanets, Igor A., Lowe, Mark E., Xiao, Xunjun, Syplyviy, Vasyliy A., Monteleone, Jon, Gargosky, Sharron, Dickinson, Klara, Martinez, Antonia, Mokhtarani, Masoud, Scharschmidt, Bruce F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733097/
https://ncbi.nlm.nih.gov/pubmed/20512995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23589
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