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Functionalization of poly(methyl methacrylate) (PMMA) as a substrate for DNA microarrays

A chemical procedure was developed to functionalize poly(methyl methacrylate) (PMMA) substrates. PMMA is reacted with hexamethylene diamine to yield an aminated surface for immobilizing DNA in microarrays. The density of primary NH(2) groups was 0.29 nmol/cm(2). The availability of these primary ami...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Fixe, F., Dufva, M., Telleman, P., Christensen, C. B. V.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373302/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14718554/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng157
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