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Functionalization of poly(methyl methacrylate) (PMMA) as a substrate for DNA microarrays

A chemical procedure was developed to functionalize poly(methyl methacrylate) (PMMA) substrates. PMMA is reacted with hexamethylene diamine to yield an aminated surface for immobilizing DNA in microarrays. The density of primary NH(2) groups was 0.29 nmol/cm(2). The availability of these primary ami...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Fixe, F., Dufva, M., Telleman, P., Christensen, C. B. V.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373302/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14718554/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng157
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