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Functionalization of poly(methyl methacrylate) (PMMA) as a substrate for DNA microarrays

A chemical procedure was developed to functionalize poly(methyl methacrylate) (PMMA) substrates. PMMA is reacted with hexamethylene diamine to yield an aminated surface for immobilizing DNA in microarrays. The density of primary NH(2) groups was 0.29 nmol/cm(2). The availability of these primary ami...

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Bibliografiske detaljer
Main Authors: Fixe, F., Dufva, M., Telleman, P., Christensen, C. B. V.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC373302/
https://ncbi.nlm.nih.gov/pubmed/14718554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gng157
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