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Echinomycin inhibits chromosomal DNA replication and embryonic development in vertebrates
Echinomycin, a member of the quinoxaline family of antibiotics, is known to be a strong inhibitor of RNA synthesis which has been attributed to its ability to bind to double-helical DNA. Here we study the effect of echinomycin upon DNA replication using egg extracts and embryos from Xenopus laevis a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC373276/ https://ncbi.nlm.nih.gov/pubmed/14704344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh166 |
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