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Unusual base pairing during the decoding of a stop codon by the ribosome
During normal translation, binding of a release factor to one of the three stop codons (UGA, UAA or UAG) results in termination of protein synthesis. However, modification of the initial uridine to a pseudouridine (Ψ) allows efficient recognition and read-through of these stop codons by a transfer R...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3732562/ https://ncbi.nlm.nih.gov/pubmed/23812587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12302 |
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