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Comparison of systemic and mucosal vaccination: impact on intravenous and rectal SIV challenge

Mucosal tissues are the primary route of transmission for most respiratory and sexually transmitted diseases, including human immunodeficiency virus. We aimed to generate strong mucosal immune responses to simian immunodeficiency virus (SIV) in rhesus macaques by targeting recombinant adenovirus ser...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bolton, DL, Song, K, Wilson, RL, Kozlowski, PA, Tomaras, GD, Keele, BF, Lovingood, RV, Rao, S, Roederer, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732474/
https://ncbi.nlm.nih.gov/pubmed/22031182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2011.45
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