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Deubiquitinases Sharpen Substrate Discrimination during Membrane Protein Degradation from the ER

Newly synthesized membrane proteins are queried by ubiquitin ligase complexes and triaged between degradative and nondegradative fates. The mechanisms that convert modest differences in substrate-ligase interactions into decisive outcomes of ubiquitination are not well understood. Here, we reconstit...

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Bibliografiset tiedot
Päätekijät: Zhang, Zai-Rong, Bonifacino, Juan S., Hegde, Ramanujan S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cell Press 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732389/
https://ncbi.nlm.nih.gov/pubmed/23890821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.06.038
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