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ATM-deficient human neural stem cells as an in vitro model system to study neurodegeneration
Loss of ATM kinase, a transducer of the DNA damage response and redox sensor, causes the neurodegenerative disorder ataxia-telangiectasia (A-T). While a great deal of progress has been made in elucidating the ATM-dependent DNA damage response (DDR) network, a key challenge remains in understanding t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3732388/ https://ncbi.nlm.nih.gov/pubmed/23707302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2013.04.013 |
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