Optimized Metabolomic Approach to Identify Uremic Solutes in Plasma of Stage 3–4 Chronic Kidney Disease Patients

BACKGROUND: Chronic kidney disease (CKD) is characterized by the progressive accumulation of various potential toxic solutes. Furthermore, uremic plasma is a complex mixture hampering accurate determination of uremic toxin levels and the identification of novel uremic solutes. METHODS: In this study...

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Hauptverfasser: Mutsaers, Henricus A. M., Engelke, Udo F. H., Wilmer, Martijn J. G., Wetzels, Jack F. M., Wevers, Ron A., van den Heuvel, Lambertus P., Hoenderop, Joost G., Masereeuw, Rosalinde
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732267/
https://ncbi.nlm.nih.gov/pubmed/23936492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071199
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