Expression of Human Gaucher Disease Gene GBA Generates Neurodevelopmental Defects and ER Stress in Drosophila Eye

Gaucher disease (GD) is the most common of the lysosomal storage disorders and is caused by defects in the GBA gene encoding glucocerebrosidase (GlcCerase). The accumulation of its substrate, glucocylceramide (GlcCer) is considered the main cause of GD. We found here that the expression of human mut...

詳細記述

保存先:
書誌詳細
主要な著者: Suzuki, Takahiro, Shimoda, Masami, Ito, Kumpei, Hanai, Shuji, Aizawa, Hidenobu, Kato, Tomoki, Kawasaki, Kazunori, Yamaguchi, Terumi, Ryoo, Hyung Don, Goto-Inoue, Naoko, Setou, Mitsutoshi, Tsuji, Shoji, Ishida, Norio
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732251/
https://ncbi.nlm.nih.gov/pubmed/23936319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069147
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料