LT-IIb(T13I), a Non-Toxic Type II Heat-Labile Enterotoxin, Augments the Capacity of a Ricin Toxin Subunit Vaccine to Evoke Neutralizing Antibodies and Protective Immunity

Currently, there is a shortage of adjuvants that can be employed with protein subunit vaccines to enhance protection against biological threats. LT-IIb(T13I) is an engineered nontoxic derivative of LT-IIb, a member of the type II subfamily of heat labile enterotoxins expressed by Escherichia coli, t...

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Autors principals: Greene, Christopher J., Chadwick, Chrystal M., Mandell, Lorrie M., Hu, John C., O’Hara, Joanne M., Brey, Robert N., Mantis, Nicholas J., Connell, Terry D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732243/
https://ncbi.nlm.nih.gov/pubmed/23936344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069678
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