Bicalutamide Activated Oncolytic Adenovirus for the Adjuvant Therapy of High Risk Prostate Cancer

Conditionally replicating adenoviruses (CRAds) utilize tissue specific promoters to control the expression of the early genes, E1A and E1B, to preferentially replicate and lyse tumor cells (oncolysis). Previous CRAds used in prostate cancer gene therapy require androgens to activate prostate specifi...

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Detalhes bibliográficos
Main Authors: Johnson, Tamara Jane, Hoti, Naser Uddin, Liu, Chunyan, Chowdhury, Wasim H., Li, Ying, Zhang, Yonggang, Lupold, Shawn E., DeWeese, Theodore, Rodriguez, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732197/
https://ncbi.nlm.nih.gov/pubmed/23764901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2013.34
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