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MEMBRANE ATTACK BY COMPLEMENT: THE ASSEMBLY AND BIOLOGY OF TERMINAL COMPLEMENT COMPLEXES

Complement system activation plays an important role in both innate and acquired immunity. Activation of complement and the subsequent formation of C5b-9 channels (the membrane attack complex) on cell membranes lead to cell death. However, when the number of channels assembled on the surface of nucl...

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Autori principali: Tegla, Cosmin A., Cudrici, Cornelia, Patel, Snehal, Trippe, Richard, Rus, Violeta, Niculescu, Florin, Rus, Horea
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732183/
https://ncbi.nlm.nih.gov/pubmed/21850539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-011-8239-5
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