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TRAIL, DR4 and DR5 Are Upregulated in Kidneys from Patients with Lupus Nephritis and Exert Proliferative and Proinflammatory Effects

We have previously reported that TRAIL is upregulated on T cells from patients with lupus and that T-cell associated TRAIL enhances autoimmune parameters in a murine model of lupus. Whether TRAIL/TRAIL-R interaction plays a role in organ involvement such as lupus nephritis has not yet been asssessed...

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Détails bibliographiques
Auteurs principaux: Nguyen, Vinh, Cudrici, Cornelia, Zernetkina, Valentina, Niculescu, Florin, Rus, Horea, Drachenberg, Cynthia, Rus, Violeta
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734543/
https://ncbi.nlm.nih.gov/pubmed/19349211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2009.02.011
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