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Modeling the evolution dynamics of exon-intron structure with a general random fragmentation process

BACKGROUND: Most eukaryotic genes are interrupted by spliceosomal introns. The evolution of exon-intron structure remains mysterious despite rapid advance in genome sequencing technique. In this work, a novel approach is taken based on the assumptions that the evolution of exon-intron structure is a...

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Detalhes bibliográficos
Main Authors: Wang, Liya, Stein, Lincoln D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732091/
https://ncbi.nlm.nih.gov/pubmed/23448166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-13-57
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