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SOCS1 gene transfer accelerates the transition to heart failure through the inhibition of the gp130/JAK/STAT pathway

AIMS: The suppressors of cytokine signalling (SOCS) are identified inhibitors of cytokine and growth factor signalling that act via the Janus kinase (JAK) signal transducers and activators of transcription (STAT) pathways. Aberrant JAK/STAT signalling promotes progression from hypertrophy to heart f...

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Autori principali: Cittadini, Antonio, Monti, Maria Gaia, Iaccarino, Guido, Castiello, Maria Carmina, Baldi, Alfonso, Bossone, Eduardo, Longobardi, Salvatore, Marra, Alberto Maria, Petrillo, Valentina, Saldamarco, Lavinia, During, Matthew John, Saccà, Luigi, Condorelli, Gianluigi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732068/
https://ncbi.nlm.nih.gov/pubmed/22875468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs261
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