Mitochondrial protectant pramipexole prevents sex-specific long-term cognitive impairment from early anaesthesia exposure in rats 

BACKGROUND: Exposure to general anaesthesia during critical stages of brain development results in long-lasting cognitive impairment. Co-administration of protective agents could minimize the detrimental effects of anaesthesia. Co-administration of R(+)pramipexole (PPX), a synthetic aminobenzothiazo...

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Hauptverfasser: Boscolo, A., Ori, C., Bennett, J., Wiltgen, B., Jevtovic-Todorovic, V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Developmental Neurotoxicity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732064/
https://ncbi.nlm.nih.gov/pubmed/23616588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bja/aet073
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