CC chemokine receptor 8 potentiates donor T(reg) survival and is critical for the prevention of murine graft-versus-host disease

The infusion of donor regulatory T cells (T(regs)) has been used to prevent acute graft-versus-host disease (GVHD) in mice and has shown promise in phase 1 clinical trials. Previous work suggested that early T(reg) migration into lymphoid tissue was important for GVHD prevention. However, it is uncl...

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Détails bibliographiques
Auteurs principaux: Coghill, James M., Fowler, Kenneth A., West, Michelle L., Fulton, LeShara M., van Deventer, Hendrik, McKinnon, Karen P., Vincent, Benjamin G., Lin, Kaifeng, Panoskaltsis-Mortari, Angela, Cook, Donald N., Blazar, Bruce R., Serody, Jonathan S.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2013
Sujets:
Transplantation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731935/
https://ncbi.nlm.nih.gov/pubmed/23798714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-435735
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