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Adeno-associated Virus-mediated, Mifepristone-regulated Transgene Expression in the Brain
Gene therapy, in its current configuration, is irreversible and does not allow control over transgene expression in case of side effects. Only few regulated vector systems are available, and none of these has reached clinical applicability yet. The mifepristone (Mfp)-regulated Gene Switch (GS) syste...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3731885/ https://ncbi.nlm.nih.gov/pubmed/23860550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.35 |
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