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Intrafollicular location of marginal zone/CD1d(hi) B cells is associated with autoimmune pathology in a mouse model of lupus

Marginal zone (MZ) B cells contain a large number of autoreactive clones and the expansion of this compartment has been associated with autoimmunity. MZ B cells also efficiently transport blood-borne antigen to the follicles where they activate T cells and differentiate into plasma cells. Using the...

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Hlavní autoři: Duan, Biyan, Niu, Haitao, Xu, Zhiwei, Sharpe, Arlene H, Croker, Byron P, Sobel, Eric S, Morel, Laurence
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731739/
https://ncbi.nlm.nih.gov/pubmed/18607347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2008.62
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