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Opposing HDAC4 nuclear fluxes due to phosphorylation by β-adrenergic activated protein kinase A or by activity or Epac activated CaMKII in skeletal muscle fibres

Class IIa histone deacetylases (HDACs) move between skeletal muscle fibre cytoplasm and nuclei in response to various stimuli, suppressing activity of the exclusively nuclear transcription factor Mef2. Protein kinase A (PKA) phosphorylates class IIa HDACs in cardiac muscle, resulting in HDAC nuclear...

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Detaylı Bibliyografya
Asıl Yazarlar: Liu, Yewei, Schneider, Martin F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731617/
https://ncbi.nlm.nih.gov/pubmed/23652597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.256263
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