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Putative pore-loops of TMEM16/anoctamin channels affect channel density in cell membranes

The recently identified TMEM16/anoctamin protein family includes Ca(2+)-activated anion channels (TMEM16A, TMEM16B), a cation channel (TMEM16F) and proteins with unclear function. TMEM16 channels consist of eight putative transmembrane domains (TMs) with TM5–TM6 flanking a re-entrant loop thought to...

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Autori principali: Adomaviciene, Aiste, Smith, Keith J, Garnett, Hannah, Tammaro, Paolo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731609/
https://ncbi.nlm.nih.gov/pubmed/23613533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.251660
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