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Serum TRPM1 Autoantibodies from Melanoma Associated Retinopathy Patients Enter Retinal ON-Bipolar Cells and Attenuate the Electroretinogram in Mice

Melanoma-associated retinopathy (MAR) is a paraneoplastic syndrome associated with cutaneous malignant melanoma and the presence of autoantibodies that label neurons in the inner retina. The visual symptoms and electroretinogram (ERG) phenotype characteristic of MAR resemble the congenital visual di...

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Bibliografiske detaljer
Main Authors: Xiong, Wei-Hong, Duvoisin, Robert M., Adamus, Grazyna, Jeffrey, Brett G., Gellman, Celia, Morgans, Catherine W.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731326/
https://ncbi.nlm.nih.gov/pubmed/23936334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069506
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