Serum TRPM1 Autoantibodies from Melanoma Associated Retinopathy Patients Enter Retinal ON-Bipolar Cells and Attenuate the Electroretinogram in Mice

Melanoma-associated retinopathy (MAR) is a paraneoplastic syndrome associated with cutaneous malignant melanoma and the presence of autoantibodies that label neurons in the inner retina. The visual symptoms and electroretinogram (ERG) phenotype characteristic of MAR resemble the congenital visual di...

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Autores principales: Xiong, Wei-Hong, Duvoisin, Robert M., Adamus, Grazyna, Jeffrey, Brett G., Gellman, Celia, Morgans, Catherine W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731326/
https://ncbi.nlm.nih.gov/pubmed/23936334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069506
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