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Inhibition of Proliferation and Induction of Autophagy by Atorvastatin in PC3 Prostate Cancer Cells Correlate with Downregulation of Bcl2 and Upregulation of miR-182 and p21

The epidemiologic association between statin use and decreased risk of advanced prostate cancer suggests that statins may inhibit prostate cancer development and/or progression. Studies were performed to determine the effects of a model statin, atorvastatin (ATO), on the proliferation and differenti...

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Hlavní autoři: Peng, Xinjian, Li, Wenping, Yuan, Liang, Mehta, Rajendra G., Kopelovich, Levy, McCormick, David L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731278/
https://ncbi.nlm.nih.gov/pubmed/23936432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070442
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