Renoprotective Effects of Atorvastatin in Diabetic Mice: Downregulation of RhoA and Upregulation of Akt/GSK3

Potential benefits of statins in the treatment of chronic kidney disease beyond lipid-lowering effects have been described. However, molecular mechanisms involved in renoprotective actions of statins have not been fully elucidated. We questioned whether statins influence development of diabetic neph...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bruder-Nascimento, Thiago, Callera, Glaucia, Montezano, Augusto Cesar, Antunes, Tayze T., He, Ying, Cat, Aurelie Nguyen Dinh, Ferreira, Nathanne S., Barreto, Pedro A., Olivon, Vânia C., Tostes, Rita C., Touyz, Rhian M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029810/
https://ncbi.nlm.nih.gov/pubmed/27649495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162731
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