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Protein destabilisation by ruthenium(II) tris-bipyridine based protein-surface mimetics,

Highly functionalised ruthenium(II) tris-bipyridine receptor 1 which acts as a selective sensor for equine cytochrome c (cyt c) is shown to destabilise the native protein conformation by around 25 °C. Receptors 2 and 3 do not exert this effect confirming the behaviour is a specific effect of molecul...

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Bibliographic Details
Main Authors: Wilson, Andrew J., Ault, James R., Filby, Maria H., Philips, Hazel I. A., Ashcroft, Alison E., Fletcher, Nicholas C.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731202/
https://ncbi.nlm.nih.gov/pubmed/23411505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3ob26251k
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