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Increased SIAH expression predicts ductal carcinoma in situ (DCIS) progression to invasive carcinoma
Hyperactivated HER2/Neu/EGFR/RAS signaling is a major growth-promoting pathway known to drive cellular transformation and oncogenesis in breast cancers. HER2 amplification is detected in ~20% of all human breast cancer and is quite prevalent (up to 49%) in ductal carcinoma in situ (DCIS). The E3 ubi...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3730842/ https://ncbi.nlm.nih.gov/pubmed/21088888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-010-1254-8 |
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