Increased SIAH expression predicts ductal carcinoma in situ (DCIS) progression to invasive carcinoma

Hyperactivated HER2/Neu/EGFR/RAS signaling is a major growth-promoting pathway known to drive cellular transformation and oncogenesis in breast cancers. HER2 amplification is detected in ~20% of all human breast cancer and is quite prevalent (up to 49%) in ductal carcinoma in situ (DCIS). The E3 ubi...

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Autori principali: Behling, Kathryn C., Tang, Amy, Freydin, Boris, Chervoneva, Inna, Kadakia, Sameep, Schwartz, Gordon F., Rui, Hallgeir, Witkiewicz, Agnieszka K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730842/
https://ncbi.nlm.nih.gov/pubmed/21088888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-010-1254-8
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