T Cells Induce Pre-Metastatic Osteolytic Disease and Help Bone Metastases Establishment in a Mouse Model of Metastatic Breast Cancer

Bone metastases, present in 70% of patients with metastatic breast cancer, lead to skeletal disease, fractures and intense pain, which are all believed to be mediated by tumor cells. Engraftment of tumor cells is supposed to be preceded by changes in the target tissue to create a permissive microenv...

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Bibliografiske detaljer
Main Authors: Monteiro, Ana Carolina, Leal, Ana Carolina, Gonçalves-Silva, Triciana, Mercadante, Ana Carolina T., Kestelman, Fabiola, Chaves, Sacha Braun, Azevedo, Ricardo Bentes, Monteiro, João P., Bonomo, Adriana
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730734/
https://ncbi.nlm.nih.gov/pubmed/23935856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068171
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