T Cells Induce Pre-Metastatic Osteolytic Disease and Help Bone Metastases Establishment in a Mouse Model of Metastatic Breast Cancer

Bone metastases, present in 70% of patients with metastatic breast cancer, lead to skeletal disease, fractures and intense pain, which are all believed to be mediated by tumor cells. Engraftment of tumor cells is supposed to be preceded by changes in the target tissue to create a permissive microenv...

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Bibliographische Detailangaben
Hauptverfasser: Monteiro, Ana Carolina, Leal, Ana Carolina, Gonçalves-Silva, Triciana, Mercadante, Ana Carolina T., Kestelman, Fabiola, Chaves, Sacha Braun, Azevedo, Ricardo Bentes, Monteiro, João P., Bonomo, Adriana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730734/
https://ncbi.nlm.nih.gov/pubmed/23935856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068171
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