Glucose starvation induces cell death in K-ras-transformed cells by interfering with the hexosamine biosynthesis pathway and activating the unfolded protein response

Cancer cells, which use more glucose than normal cells and accumulate extracellular lactate even under normoxic conditions (Warburg effect), have been reported to undergo cell death under glucose deprivation, whereas normal cells remain viable. As it may be relevant to exploit the molecular mechanis...

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Detaylı Bibliyografya
Asıl Yazarlar: Palorini, R, Cammarata, F, Balestrieri, C, Monestiroli, A, Vasso, M, Gelfi, C, Alberghina, L, Chiaradonna, F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2013
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730427/
https://ncbi.nlm.nih.gov/pubmed/23868065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.257
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