Glucose starvation induces cell death in K-ras-transformed cells by interfering with the hexosamine biosynthesis pathway and activating the unfolded protein response

Cancer cells, which use more glucose than normal cells and accumulate extracellular lactate even under normoxic conditions (Warburg effect), have been reported to undergo cell death under glucose deprivation, whereas normal cells remain viable. As it may be relevant to exploit the molecular mechanis...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Palorini, R, Cammarata, F, Balestrieri, C, Monestiroli, A, Vasso, M, Gelfi, C, Alberghina, L, Chiaradonna, F
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730427/
https://ncbi.nlm.nih.gov/pubmed/23868065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.257
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky