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Modifying chemotherapy response by targeted inhibition of eukaryotic initiation factor 4A

Translation is regulated predominantly at the initiation phase by several signal transduction pathways that are often usurped in human cancers, including the PI3K/Akt/mTOR axis. mTOR exerts unique administration over translation by regulating assembly of eukaryotic initiation factor (eIF) 4F, a hete...

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Detalhes bibliográficos
Main Authors: Cencic, R, Robert, F, Galicia-Vázquez, G, Malina, A, Ravindar, K, Somaiah, R, Pierre, P, Tanaka, J, Deslongchamps, P, Pelletier, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730203/
https://ncbi.nlm.nih.gov/pubmed/23872707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2013.25
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