HSP90 Inhibitor SNX5422/2112 Targets the Dysregulated Signal and Transcription Factor Network and Malignant Phenotype of Head and Neck Squamous Cell Carcinoma

Heat shock protein 90 (HSP90) is a chaperone protein that stabilizes proteins involved in oncogenic and therapeutic resistance pathways of epithelial cancers, including head and neck squamous cell carcinomas (HNSCCs). Here, we characterized the molecular, cellular, and preclinical activity of HSP90...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Friedman, Jay A, Wise, Stephanie C, Hu, Michael, Gouveia, Chris, Vander Broek, Robert, Freudlsperger, Christian, Kannabiran, Vishnu R, Arun, Pattatheyil, Mitchell, James B, Chen, Zhong, Van Waes, Carter
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Neoplasia Press Inc. 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730018/
https://ncbi.nlm.nih.gov/pubmed/23908686
Tagiau: Ychwanegu Tag
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