Loss of Survivin in the Prostate Epithelium Impedes Carcinogenesis in a Mouse Model of Prostate Adenocarcinoma

The inhibitor of apoptosis protein survivin is expressed in most cancers. Using the conditional PTEN deletion mouse model, we previously reported that survivin levels increase with prostate tumor growth. Here we evaluated the functional role of survivin in prostate tumor growth. First, we demonstrat...

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Detalhes bibliográficos
Main Authors: Adisetiyo, Helty, Liang, Mengmeng, Liao, Chun-Peng, Aycock-Williams, Ari, Cohen, Michael B., Xu, Shili, Neamati, Nouri, Conway, Edward M., Cheng, Chieh-Yang, Nikitin, Alexander Yu., Roy-Burman, Pradip
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729965/
https://ncbi.nlm.nih.gov/pubmed/23936028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069484
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