Loss of Survivin in the Prostate Epithelium Impedes Carcinogenesis in a Mouse Model of Prostate Adenocarcinoma

The inhibitor of apoptosis protein survivin is expressed in most cancers. Using the conditional PTEN deletion mouse model, we previously reported that survivin levels increase with prostate tumor growth. Here we evaluated the functional role of survivin in prostate tumor growth. First, we demonstrat...

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Autori principali: Adisetiyo, Helty, Liang, Mengmeng, Liao, Chun-Peng, Aycock-Williams, Ari, Cohen, Michael B., Xu, Shili, Neamati, Nouri, Conway, Edward M., Cheng, Chieh-Yang, Nikitin, Alexander Yu., Roy-Burman, Pradip
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729965/
https://ncbi.nlm.nih.gov/pubmed/23936028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069484
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