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A Role for the Protein Tyrosine Phosphatase CD45 in Macrophage Adhesion through the Regulation of Paxillin Degradation

CD45 is a protein tyrosine phosphatase expressed on all cells of hematopoietic origin that is known to regulate Src family kinases. In macrophages, the absence of CD45 has been linked to defects in adhesion, however the molecular mechanisms involved remain poorly defined. In this study, we show that...

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Detalhes bibliográficos
Main Authors: St-Pierre, Joëlle, Ostergaard, Hanne L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729947/
https://ncbi.nlm.nih.gov/pubmed/23936270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071531
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