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Effect of oral sodium bicarbonate supplementation on progression of chronic kidney disease in patients with chronic metabolic acidosis: study protocol for a randomized controlled trial (SoBic-Study)
BACKGROUND: Overt chronic metabolic acidosis in patients with chronic kidney disease develops after a drop of glomerular filtration rate to less than approximately 25 mL/min/1.73 m(2). The pathogenic mechanism seems to be a lack of tubular bicarbonate production, which in healthy individuals neutral...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3729547/ https://ncbi.nlm.nih.gov/pubmed/23826760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-14-196 |
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