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Creating diseases to understand what prevents them: genetic analysis of inflammation in the gastrointestinal tract

Inflammatory bowel diseases (IBD), including both ulcerative colitis and Crohn’s disease, are extremely variable in severity and have strong genetic components. In mice, several mutations are known to favor or inhibit intestinal inflammation. But a comprehensive picture of the pathogenesis of IBD ca...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Brandl, Katharina, Beutler, Bruce
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729218/
https://ncbi.nlm.nih.gov/pubmed/23123276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2012.10.005
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