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Creating diseases to understand what prevents them: genetic analysis of inflammation in the gastrointestinal tract

Inflammatory bowel diseases (IBD), including both ulcerative colitis and Crohn’s disease, are extremely variable in severity and have strong genetic components. In mice, several mutations are known to favor or inhibit intestinal inflammation. But a comprehensive picture of the pathogenesis of IBD ca...

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Detalhes bibliográficos
Main Authors: Brandl, Katharina, Beutler, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729218/
https://ncbi.nlm.nih.gov/pubmed/23123276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2012.10.005
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