Terminal axon branching is regulated by the LKB1-NUAK1 kinase pathway via presynaptic mitochondrial capture

The molecular mechanisms underlying the axon arborization of mammalian neurons are poorly understood but are critical for the establishment of functional neural circuits. We identified a pathway defined by two kinases, LKB1 and NUAK1, required for cortical axon branching in vivo. Conditional deletio...

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Hauptverfasser: Courchet, Julien, Lewis, Tommy, Lee, Sohyon, Courchet, Virginie, Liou, Deng-Yuan, Aizawa, Shinichi, Polleux, Franck
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729210/
https://ncbi.nlm.nih.gov/pubmed/23791179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.05.021
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