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MFF-dependent mitochondrial fission regulates presynaptic release and axon branching by limiting axonal mitochondria size

Neurons display extreme degrees of polarization, including compartment-specific organelle morphology. In cortical, long-range projecting, pyramidal neurons (PNs), dendritic mitochondria are long and tubular whereas axonal mitochondria display uniformly short length. Here we explored the functional s...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Lewis, Tommy L., Kwon, Seok-Kyu, Lee, Annie, Shaw, Reuben, Polleux, Franck
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258764/
https://ncbi.nlm.nih.gov/pubmed/30479337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07416-2
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