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CYP2B6 and bupropion’s smoking cessation pharmacology: the role of hydroxybupropion
Bupropion is indicated to promote smoking cessation. Animal studies suggest that bupropion’s major metabolite hydroxybupropion can mediate bupropion’s pharmacologic activity. We measured plasma bupropion and metabolite levels in a double-blind, placebo controlled, randomized smoking cessation trial....
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3729209/ https://ncbi.nlm.nih.gov/pubmed/23149928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2012.186 |
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