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Hemoglobin degradation in malaria-infected erythrocytes determined from live cell magnetophoresis

During intra-erythrocytic development, malaria trophozoites digest hemoglobin, which leads to parasite growth and asexual replication while accumulating toxic heme. To avoid death, the parasite synthesizes insoluble hemozoin crystals in the digestive vacuole through polymerization of β-hematin dimer...

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Detalles Bibliográficos
Main Authors: Moore, Lee R., Fujioka, Hisashi, Williams, P. Stephen, Chalmers, Jeffrey J., Grimberg, Brian, Zimmerman, Peter, Zborowski, Maciej
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728832/
https://ncbi.nlm.nih.gov/pubmed/16461330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.05-5122fje
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