Hemoglobin degradation in malaria-infected erythrocytes determined from live cell magnetophoresis

During intra-erythrocytic development, malaria trophozoites digest hemoglobin, which leads to parasite growth and asexual replication while accumulating toxic heme. To avoid death, the parasite synthesizes insoluble hemozoin crystals in the digestive vacuole through polymerization of β-hematin dimer...

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Bibliografiske detaljer
Main Authors: Moore, Lee R., Fujioka, Hisashi, Williams, P. Stephen, Chalmers, Jeffrey J., Grimberg, Brian, Zimmerman, Peter, Zborowski, Maciej
Format: Artigo
Sprog:Inglês
Udgivet: 2006
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728832/
https://ncbi.nlm.nih.gov/pubmed/16461330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.05-5122fje
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