CORIN OVEREXPRESSION IMPROVES CARDIAC FUNCTION, HEART FAILURE AND SURVIVAL IN MICE WITH DILATED CARDIOMYOPATHY

Heart failure, caused by dilated cardiomyopathy and other cardiac disorders such as hypertension, is a major public health problem with high morbidity and mortality. Corin, a cardiac enzyme that cleaves natriuretic peptides, is a promising biomarker of cardiomyopathy and heart failure—but its functi...

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Hauptverfasser: Gladysheva, Inna P., Wang, Dong, McNamee, Rachel, Houng, Aiilyan K., Mohamad, Almois, Fan, T. Michael, Reed, Guy L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728819/
https://ncbi.nlm.nih.gov/pubmed/23232642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.112.193631
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