p63 Regulates Adult Neural Precursor and Newly Born Neuron Survival to Control Hippocampal-Dependent Behavior

The molecular mechanisms that regulate adult neural precursor cell (NPC) survival, and thus maintain adult neurogenesis, are not well defined. Here, we investigate the role of p63, a p53 family member, in adult NPC function in mice. Conditional ablation of p63 in adult NPCs or p63 haploinsufficiency...

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Detalhes bibliográficos
Main Authors: Cancino, Gonzalo I., Yiu, Adelaide P., Fatt, Michael P., Dugani, Chandrasagar B., Flores, Elsa R., Frankland, Paul W., Josselyn, Sheena A., Miller, Freda D., Kaplan, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728680/
https://ncbi.nlm.nih.gov/pubmed/23904595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1251-13.2013
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