Nuclear MTA1 overexpression is associated with aggressive prostate cancer, recurrence and metastasis in African Americans

Metastasis-associated protein 1 (MTA1), a negative epigenetic modifier, plays a critical role in prostate cancer (PCa) progression. We hypothesized that MTA1 overexpression in primary tumor tissues can predict PCa aggressiveness and metastasis. Immunohistochemical staining of MTA1 was done on archiv...

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Main Authors: Dias, Steven J., Zhou, Xinchun, Ivanovic, Marina, Gailey, Michael P., Dhar, Swati, Zhang, Liangfen, He, Zhi, Penman, Alan D., Vijayakumar, Srinivasan, Levenson, Anait S.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728596/
https://ncbi.nlm.nih.gov/pubmed/23900262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02331
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